According to the new research study of scientist Terry Combs there is possibility to lower blood glucose level in type-1 diabetes.

In earlier time it was believed that insulin is susceptible to gastric juice. it gets degraded into the acidic environment of the stomach. so couldn't be delivered orally - hence the dependence on insulin injections. But this new mid-stage trial suggests for the first time that given the right dose, insulin tablets could really work.

The new insulin pills work by using a protective coating and a high-enough dose of insulin so that most of it can get destroyed in the digestive tract, and it will still deliver a beneficial amount of the hormone to the bloodstream.

It can be also formulated as sustained release dosage forms to reduce the frequency of dosing.

Clinical trial:

According to report of ScienceAlert,

In a 28-day trial, the Oramed researchers took 180 patients with type 2 diabetes who were no longer responding adequately to metformin - a first-line medication given to people when they're diagnosed with the condition.

Before bed, they were either given the insulin pill - which has been called ORMD-0801 - or a placebo, and their overnight glucose levels were monitored. Those who were given the oral insulin had a mean night-time glucose reduction of nearly 6.5 percent compared to the placebo group.

Promisingly, there weren't any serious side effects reported, and no issues with the blood sugar levels dropping too low.

According to the ORAMED phase III is being conducted shortly & if the results obtained from it would be promising & satisfactory, we might alternate the insulin injections with these new pills.

It is no yet any evidence of successful working of these pills for type-2 diabetes same as type-1 diabetes. but there would be more research conducted on this.

So there would be needle less treatment for type-1 diabetes in future.

Published by Ridhdhesh Jivawala