Antibiotic resistance is a growing concern in medicine, and there are plenty of researchers trying to better understand the phenomenon.

By better understanding infectious diseases and the way they work, scientists can develop more effective vaccinations and treatments. There are a huge number of studies that have been carried out in the field, and scientific knowledge is steadily improving. However there remains a lot more work to be done.

One recent study by a team at the University of Idaho has provided significant insight into the causes of antibiotic resistance. Eva Top, professor in the Department of Biological Sciences in the College of Science, a researcher at University of Idaho's Institute for Bioinformatics and Evolutionary Studies (IBEST) and director of the Bioinformatics and Computational Biology graduate program, and her team discovered that two genetic mutations could be crucial to understanding antibiotic resistance.

Pieces of DNA known as plasmids are key contributors to antibiotic resistance, and the study examined why some bacteria hold on to plasmids and others don’t. Top and her team found that genetic mutations caused bacteria to retain resistance plasmids, an interesting advance in the field and one that could help to slow or stop antibiotic resistance from proliferating.

While plasmids can explain some resistance, bacteria can also evolve through mutations in their chromosomes. However plasmids can make bacteria resistant to multiple drugs at one time, even those that the bacteria has never seen before. Now that scientists understand plasmids better, they can start researching ways of counteracting their effects. The next step for researchers is to find a way to make bacteria drop the plasmids that make them resistant to antibiotics.

Vaccine research is an incredibly important area of science, and it is important for researchers to choose the right clinical research organization (CRO). INC Research is a highly experienced CRO with extensive experience in the field. Whether you are carrying out clinical disease research for children or for adults, INC Research has worked on the development of antivirals, antibacterials, antifungals and vaccines.

The staff at INC Research includes a dedicated Infectious Disease Therapeutic Area team, which counts on four Infectious Disease board certified physicians, microbiologist and operational teams. Previously the company has carried out studies into infectious diseases around the world, including vaccine trials for Zika virus, Ebola virus and other global health issues.

If you are a researcher interested in tackling some of the emerging threats to global health, there is no CRO better equipped for the job than INC Research. Whether it is antibiotic resistance or any other infectious disease area that you want to look into, the company has the right expertise to help you achieve your goals.



Published by Arina Smith