The name Hypochromasia is made up of two sub-words-Hypo and Chromasia. As the name suggests, Hypo means deficiency and chromasia means color. Hypochromasia is a condition where more than half of the cells have central pallor region. It can also be used to understand a condition where the central pallor region increases. The above condition leads to a decreased production of Hemoglobin caused by lack of enough iron in the body.  What this means is that someone will develop Hypochromic anemia. Consequently, the concentration of Hemoglobin in relation to the required concentration to volume ratio of the cell will be less.

In simple terms, Hypochromasia is an indication that red blood cells have less hemoglobin than the normal requirement. The name is used in two contexts. One of them is as a descriptor of RBC on a blood smear. The main point of note is the appearance of red blood cells with a thin rim of cytoplasm which is as a result of less hemoglobin. This leads to an increased central pallor. The other context is to donate a MCHC below the reference interval.

What causes Hypochromasia?

There are two main causes of Hypochromasia. One of the main causes is the Defective Hemoglobin production which can also occur as a result of several things. Defective hemoglobin production can be an inherited defect, iron deficiency, copper deficiency and several other causes.

  • Inherited defect-These are basically a result of genetic mutation that in most cases result in abnormal production of the glob in chains. This is not verified in animals and is thought to only affect humans. In humans, they are called thalassemias.
  • Iron Deficiency-Iron is an essential component that is very important in the production of hemoglobin. If your body has less iron, then it may produce less hemoglobin. Iron deficiency is basically caused by recurrent blood loss from the gastrointestinal tract.
  • Copper deficiency-Iron without copper is not useful in the production of hemoglobin. It is especially required for utilization of iron. Copper deficiency can sometimes manifest itself as iron deficiency anemia.
  • Other causes-Other main causes of Hypochromasia include lack of vitamin B6 or Pyridoxal. It is an essential cofactor for the enzyme that is used to catalyze the first stage of the heme synthesis path ways.

Hypochromasia symptoms

Some of the most common symptoms of Hypochromasia include tiredness and fatigue caused by decreased blood concentration in the body. The other symptom is general and unexplained weakness and it also disturbed sleep cycle. Patients may find it difficult to sleep. The skin can also be pale due to less hemoglobin in the body. Sore mouth also develops when this condition is at peak.

Treatment for Hypochromasia

There are several treatment options that can be used to treat the condition. One of them is administration of Carbonyxl iron to fulfill iron deficiency. Vitamin B6 is also recommended for those who want to treat the condition as soon as possible. Homeopathic remedy can be beneficial in case the condition is caused by a parasitic infection. Quit excessive consumption of alcohol and smoking to sustain the body defense mechanism.